[Date Prev][Date Next] [Chronological] [Thread] [Archive Top]

RE: [cdn-nucl-l] Mo-99 in CANDU; "Cyclotrons to be 'hijacked' to solve isotope crisis"



UNRESTRICTED | ILLIMITÉ

Thanks Jeremy,
 
Sounds like neither the photofission method nor the gamma-n method are suitable for use with existing automated mini-processing systems, such as used for F19 (which I guess is not surprising either...)
 
Likewise, it doesn't sound like existing hospital cyclotrons are of any use in either of these schemes.

Jaro
^^^^^^^^^^^^^^^^^^^^

-----Original Message-----
From: cdn-nucl-l-admin@mailman1.cis.McMaster.CA [mailto:cdn-nucl-l-admin@mailman1.cis.McMaster.CA]On Behalf Of Whitlock, Jeremy
Sent: November 10, 2009 10:55 AM
To: JERRY CUTTLER; multiple cdn
Subject: RE: [cdn-nucl-l] Mo-99 in CANDU; "Cyclotrons to be 'hijacked' to solve isotope crisis"

UNRESTRICTED | ILLIMITÉ

The TRIUMF proposal exploits photofission in U238, using an electron linac to produce high-energy bremsstrahlung photons.  An alternative accelerator-based method exploits the gamma-n reaction in Mo-100.
 
Advantage of the photofission method:  higher specific activity, similar radiochemistry to current reactor-based method
Advantage of the gamma-n method:  higher overall yield (but lower specific activity, and new processing technique required)
 
Neither comes close to the reactor fission-product method for both yield and specific activity.
 
More general info on methods: http://www.csnm-scmn.ca/PDF/2009speaker_Ruth.pdf
 
More technical background: http://www.collectionscanada.gc.ca/eppp-archive/100/200/301/atomic_energy_canada/aecl_reports/1998/AECL-11949.pdf
 
Jeremy Whitlock
-----Original Message-----
From: cdn-nucl-l-admin@mailman1.cis.McMaster.CA [mailto:cdn-nucl-l-admin@mailman1.cis.McMaster.CA]On Behalf Of JERRY CUTTLER
Sent: Tuesday, November 10, 2009 9:59 AM
To: multiple cdn
Subject: [cdn-nucl-l] Mo-99 in CANDU; "Cyclotrons to be 'hijacked' to solve isotope crisis"

Hi Jaro,
 
PET scans are better (more accurate) than SPEC scans because they also measure coincidence.  But the half-lives of suitable positron-emitters are very short.
 
Enormous amounts of Mo-99 can be produced in a CANDU reactor by irradiating MAPLE-type "target" elements in several modified fuel bundles, but AECL is focused on bringing back the NRU reactor ASAP.
 
I submitted such a proposal to the Isotope Expert Review Panel (one of 22 Expressions of Interest).  The ERP is supposed to make its recommendation before November 30.
 
Jerry Cuttler
jerrycuttler@rogers.com
 

From: Jaro Franta <jaro-10kbq@sympatico.ca>
To: multiple cdn <cdn-nucl-l@mailman1.cis.McMaster.CA>
Sent: Tue, November 10, 2009 6:48:34 AM
Subject: [cdn-nucl-l] "Cyclotrons to be 'hijacked' to solve isotope crisis"

Interesting.
I thought that these little cyclotrons can only produce significant
quantities of proton-rich isotopes like F-19, not neutron-rich ones like
Tc-99m.
Plus of course their automated mini-processing systems are not set up for
it....
See also http://www.cns-snc.ca/branches/quebec/slowpoke/CHUS_forensique.html


Jaro
^^^^^^^^^^^^^^^^^^^^^^^^^


http://www.montrealgazette.com/health/Cyclotrons+hijacked+solve+isotope+cris
is/2204503/story.html
Cyclotrons to be 'hijacked' to solve isotope crisis
Canwest News Service, November 10, 2009 3:06 AM
 
Researchers plan to "hijack" cyclotrons in major medical centres across
Canada in a bid to generate rare isotopes and help solve the country's
nuclear medicine crisis.

"We hope to have something that we can start putting into people within two
years," said physicist Timothy Meyer at TRIUMF, a Vancouver-based physics
research centre and partner in the $1.3-million project approved by federal
agencies yesterday.

The project, the largest of several looking at short-term solutions to the
isotope crisis, will use cyclotrons at universities and medical suppliers to
try produce isotope technetium-99m, a key isotope used in nuclear medicine.

The project promises a local, short-term solution to the isotope shortage,
he said, one that could help tide the country over until a more permanent
solution is found.

"It could meet localized pockets of high demand," he said, noting that
cyclotrons in Montreal, Sherbrooke, Toronto, Edmonton and Vancouver could be
redirected to produce technetium-99m.












_______________________________________________
cdn-nucl-l mailing list
cdn-nucl-l@mailman.McMaster..CA
http://mailman.McMaster.CA/mailman/listinfo/cdn-nucl-l



CONFIDENTIAL AND PRIVILEGED INFORMATION NOTICE

This e-mail, and any attachments, may contain information that
is confidential, subject to copyright, or exempt from disclosure.
Any unauthorized review, disclosure, retransmission, 
dissemination or other use of or reliance on this information 
may be unlawful and is strictly prohibited.  

AVIS D'INFORMATION CONFIDENTIELLE ET PRIVILÉGIÉE

Le présent courriel, et toute pièce jointe, peut contenir de 
l'information qui est confidentielle, régie par les droits 
d'auteur, ou interdite de divulgation. Tout examen, 
divulgation, retransmission, diffusion ou autres utilisations 
non autorisées de l'information ou dépendance non autorisée 
envers celle-ci peut être illégale et est strictement interdite.



CONFIDENTIAL AND PRIVILEGED INFORMATION NOTICE

This e-mail, and any attachments, may contain information that
is confidential, subject to copyright, or exempt from disclosure.
Any unauthorized review, disclosure, retransmission, 
dissemination or other use of or reliance on this information 
may be unlawful and is strictly prohibited.  

AVIS D'INFORMATION CONFIDENTIELLE ET PRIVILÉGIÉE

Le présent courriel, et toute pièce jointe, peut contenir de 
l'information qui est confidentielle, régie par les droits 
d'auteur, ou interdite de divulgation. Tout examen, 
divulgation, retransmission, diffusion ou autres utilisations 
non autorisées de l'information ou dépendance non autorisée 
envers celle-ci peut être illégale et est strictement interdite.