Re: [cdn-nucl-l] Alpha particles on cells, non-linear effect

["Philippe Duport" <pduport@uottawa.ca>]

The reference for the paper Jim is referring to is

"The oncogenic transforming potential of the passage of single alpha
particles through mammalian cell nuclei.  R.C. Miller et al., Proc. Natl.
Acad. Sci.UAS.  Vol. 96, 19-22 (1999).

Philippe Duport
pdupor@uottawa.ca

----- Original Message -----
From: "Jerry Cuttler" <jerrycuttler@home.com>
To: "cdn-nucl-l" <cdn-nucl-l@informer2.cis.McMaster.CA>
Sent: Thursday, January 25, 2001 1:16 PM
Subject: [cdn-nucl-l] Alpha particles on cells, non-linear effect


>
> ----- Original Message -----
> From: Bernard L Cohen <blc+@pitt.edu>
> To: Multiple recipients of list ans-pie <ans-pie@nuke-ans.org>
> Sent: Thursday, January 25, 2001 9:45 AM
> Subject: Re: DU
>
>
> >
> > On Wed, 24 Jan 2001, Muckerheide wrote:
> >
> > > Scientists from a
> > > government-funded medical research laboratory at Harwell in
Oxfordshire
> > > have produced the first direct proof that a single alpha particle
> emitted
> > > by uranium can damage human cells. The damage, they say, is a crucial
> step
> > > in the development of tumours.
> >
> > --No one has ever doubted that a single alpha particle can damage
> > a cell, or even that it can initiate a cancer. But it can also stimulate
> > the immune system and stimulate production of repair enzymes which
protect
> > against cancer. Billions of similar cell damage events take place in our
> > bodies every day, so protecting against these may be a more important
> > effect of the alpha particle than adding one more initiating event.
> > Incidently, there is nothing new about finding that a single alpha
> > particle can cause such damage. For example the Columbia University
group
> > reported this a year or two ago, but they also reported that the damage
> > done by one alpha particle is substantially less than 1/N times the
damage
> > done by N alpha particles, This is contrary to the prediction of
linear-no
> > threshold theory (LNT), indicating that LNT substantially over-estimates
> > the risk from low level radiation.
> >
>
>
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